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IMPOTENCE NASAL SPRAY
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There is a new impotence drug that is now being tested which has been shown to help men who don’t respond, or can’t take, the commonly used drugs like Viagra and Levitra.
But what makes it so different, is that this impotence drug is a nasal spray. Even though the prescription medicines for impotence have achieved a kind of superstar status, they are not the end all be all for the 30 million American men who suffer from the problem. Only ten percent of them actually seek help.
According to Dr. Perry Molinoff, impotence researcher at Palatin Technologies, “About 50 percent of men who fill a prescription for a PD-5 inhibitor, do not renew it. And so whether they are not renewing it because it didn’t work or because it wasn’t well tolerated is a subject that has to be looked at in more detail.”
As a result, there remains a large untapped market of men who seek initial, or better treatment for impotence. Now researchers at Palatin, a small biotech company in Central New Jersey, have developed this nasal spray that could be the next great medicine for impotence. The medication was developed when University of Arizona researchers were looking at an experimental sunless tanning molecule called MT2. “When they gave MT2 to volunteers for skin they did get some skin tanning but they also got sexual arousal,” recalls Dr. Perry.
Palatin bought the molecule and has since created an impotence drug that is aimed solely at improving potency and sexual excitation. Now, at this week’s American Urological Association meeting, researchers showed the impotence drug, now called PT-141, is highly effective at treating impotence. The impotence drug stimulates receptors in the brain called melanocortin receptors. They’re responsible for body weight regulation and sexual arousal. In the group that got the highest dose, two-thirds had much better potency. “It’s taken by intranasal spray and it will usually have an effect within 30 minutes after taking the dose,” says Perry. “Many of them reported the ability to have intercourse going out to six or even eight hours after taking the drug.”
The developers are saying they hope the FDA will approve the new impotence drug in the next two to three years. Right now, one can only get it in studies, which are being done to make sure taking the medicine is safe.
The researchers say that even though the impotence drug can last as long as 8 hours after taking it, it is out of the blood system within four to six hours. The best guess is, the brain levels remain elevated, which accounts for its prolonged potency effects.
Dr. Molinoff says, even though PT-141 is designed to be used alone, if used with Viagra, it might work even better. And, it’s believed, because it acts in the brain, men aren’t the only ones who might benefit from the impotence drug. “So I think there’s a lot of possibility that activating the same pathway going from the hypothalamus will have the same effect on sexual arousal in women as well as in men,” believes Perry.
For more information on PT-141, click here:
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For more information on impotence, click here
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